益气活血化痰法对气虚血瘀痰阻型医院获得性肺炎患者炎症因子、 动脉血气及免疫功能的影响

Objective: To explore the effect of Yiqi Huoxue Huatan therapy on the treatment of patients with Qi deficiency and phlegm and blood stasis type hospital acquired pneumonia (HAP) and its effect on inflammatory factors, arterial blood gas and immune function. Methods: 84 cases of HAP patients who were treated in our hospital from January 2017 to January 2018 were selected.The patients were divided into the control group and the observation group according to the random digital table method, and all the two groups were 42 cases. The control group using conventional western medicine treatment, the observation group on the basis of treatment with Yiqi Huoxue Huatan therapy. The scores of TCM symptom scores, acute physiology and chronic health evaluation II (APACHE II), arterial partial pressure of oxygen (Pa02), arterial partial pressure of carbon dioxide (PaC02), hypersensitive C reactive protein (hs-CRP), tumor necrosis factor -a (TNF-a), interleukin 6 (IL-6), procalcitonin (PCT), immunoglobulin (Ig G, Ig M, I g A)were compared before and after treatment of the two groups, the adverse reactions of the two groups were compared. Results: After treatment, the level of Pa02 in the two groups was significantly higher, and the TCM symptom scores, APACHE П scores, PaC02, hs-CRP, TNP-a, IL-6 and PCT were significantly reduced (P<0.05). After treatment, the level of Pa02 in the observation group was higher than that of the control group, the TCM symptom scores, the APACHE II score, PaC02, hs-CRP, TNF-a, IL-6 and PCT were lower than those of the control group (P< 0.05). After treatment, the levels of Ig G and Ig M in the observation group increased significantly, which was higher than that in the control group (P<0.05). No obvious adverse reactions were observed in the two groups during the treatment. Conclusion: Yiqi Huoxue Huatan therapy can effectively treat HAP patients due to deficiency of vital energy, blood stasis and phlegm type, which can significantly improve arterial blood gas, immune function and inflammatory factors, and has no obvious adverse reactions. [ABSTRACT FROM AUTHOR]