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Nonspecific Uptake of 68Ga-Prostate-Specific Membrane Antigen in Diseases other than Prostate Malignancy on Positron Emission Tomography/Computed Tomography Imaging: A Pictorial Assay and Review of Literature.

Authors :
Malik, Dharmender
Sood, Apurva
Mittal, Bhagwant Rai
Singh, Harmandeep
Basher, Rajender Kumar
Shukla, Jaya
Bhattacharya, Anish
Singh, Shrawan Kumar
Source :
Indian Journal of Nuclear Medicine. Oct-Dec2018, Vol. 33 Issue 4, p317-325. 9p.
Publication Year :
2018

Abstract

68Ga-labeled prostate-specific membrane antigen (PSMA) ligand positron emission tomography/computed tomography imaging (PET/CT) is a rapidly evolving imaging modality for prostate cancer. Many studies have proved its superiority in staging, restaging, and detecting the recurrent prostate cancer. However, case reports describing the incidental tracer uptake in benign and nonprostatic malignancies are also reported in the literature, thus questioning the specificity of the tracer. This pictorial assay illustrates the nonspecific tracer uptake encountered during PSMA PET/CT imaging, knowledge of which can increase the confidence of interpreting physicians and may also open a new path for peptide receptor radionuclide therapy in nonprostatic malignancies. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09723919
Volume :
33
Issue :
4
Database :
Academic Search Index
Journal :
Indian Journal of Nuclear Medicine
Publication Type :
Academic Journal
Accession number :
132351657
Full Text :
https://doi.org/10.4103/ijnm.IJNM_81_18