神经内镜下垂体腺瘤假包膜切除的临床、病理研究.

Objective To provide a clinical reference for the necessity of surgical removal of pseudocapsule of pituitary adenoma through the pathological study of pseudocapsule and clinical data analysis of pituitary adenoma resected by neuroendoscopy.Methods 38 patients were divided into the neuroendoscopic operation group and the microscope operation group.The pseudocapsule was excised in neuroendoscopic operation group.The microscope operation group did not excise pseudocapsule.Then a pathological examination of the pseudocapsule was taken to confirm whether there was pituitary adenoma tissue in the pseudocapsule.It was compared in two groups that the residual recurrence rate and functional hormone change after three months.Results There were tumor tissue in pseudocapsule of pituitary adenoma.The residual recurrence rate of neuroendoscopic operation group(11.1%) was significantly lower than that of the microscope group(45.0%) after 3 months.Functional pituitary adenoma:The normal rate of functional hormone in microscope operation group (30.8%) is lower than that in the neuroendoscopic operation group (66.7%).Conclusions There was pituitary adenoma tissue in the pseudocapsule of pituitary adenoma.By the neuroendoscopy,the pseudocapsule of pituitary adenoma can be removed.The removal of pseudocapsule can reduce the residual recurrence rate of pituitary adenoma. [ABSTRACT FROM AUTHOR]