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Seasonality in bipolar disorder: Effect of sex and age.
- Source :
-
Journal of Affective Disorders . Jan2019, Vol. 243, p322-326. 5p. - Publication Year :
- 2019
-
Abstract
- <bold>Background: </bold>Mood episodes in bipolar disorder (BD) are reported to exhibit a seasonal pattern (SP). However, it is unclear whether this pattern is influenced by a patient's sex and age.<bold>Methods: </bold>In this nationwide registry study, we examined all inpatient treatments due to a manic (F31.0-2), depressive (F31.3-5) or mixed (F31.6) BD-episode in Austria for 2001-2014. Calculations were based on directly age-standardized rates and seasonality was analyzed on a monthly basis.<bold>Results: </bold>The database comprised 60,607 admissions (35.8% men). SP were shown for women during manic (summer-autumn), depressive (winter) and mixed (summer) episodes, for men only during manic (summer) episodes. However, no significant sex differences (manic p = 0.101, depressive p = 0.295, mixed p = 0.622 episode) were found. Women at young age (15-35 years) seemed to be more vulnerable to a SP in manic and mixed episodes.<bold>Limitations: </bold>Only aggregated patient data of inpatient treatments and no single case histories were available.<bold>Conclusions: </bold>In this nationwide registry study, a distinct SP could be shown for manic episodes in men and women, as well as a SP for depressive and mixed episodes in women. As no significant difference in any BD-subgroup could be observed, the effect of sex on the SP seems to be small, if existing at all. However, when taking age into account, we observed a higher likelihood for a SP in young women. Single case studies with information on possible further influencing factors (e.g. medication use) might help to clarify the impact of sex and age on SP in more detail. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01650327
- Volume :
- 243
- Database :
- Academic Search Index
- Journal :
- Journal of Affective Disorders
- Publication Type :
- Academic Journal
- Accession number :
- 132288841
- Full Text :
- https://doi.org/10.1016/j.jad.2018.09.073