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Human Enzymes for Organic Synthesis.

Authors :
Winkler, Margit
Geier, Martina
Hanlon, Steven P.
Nidetzky, Bernd
Glieder, Anton
Source :
Angewandte Chemie International Edition. Oct2018, Vol. 57 Issue 41, p13406-13423. 18p.
Publication Year :
2018

Abstract

Abstract: Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism of drugs and xenobiotics. Some of these reactions have been explored on the preparative scale. The major field of application of human enzymes is currently drug development, where they are applied for the synthesis of drug metabolites. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14337851
Volume :
57
Issue :
41
Database :
Academic Search Index
Journal :
Angewandte Chemie International Edition
Publication Type :
Academic Journal
Accession number :
132167979
Full Text :
https://doi.org/10.1002/anie.201800678