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New 3-(4-Propoxybenzyl)-5-Sulfanyl-Substituted (4 H)-1,2,4-Triazoles and Their Antitumor Activity.

Authors :
Ovsepyan, T.
Dilanyan, S.
Arsenyan, F.
Muradyan, R.
Minasyan, N.
Melik-Ohanjanyan, R.
Source :
Pharmaceutical Chemistry Journal. Aug2018, Vol. 52 Issue 5, p404-407. 4p.
Publication Year :
2018

Abstract

3,4-Substituted-(4 H)-1,2,4-triazole-5-thiols were synthesized and used for S-alkylation, cyanoethylation, and aminomethylation to produce a series of new 1,2,4-triazole derivatives of interest as biologically active compounds. The antitumor properties of several of the 1,2,4-triazole derivatives were studied. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0091150X
Volume :
52
Issue :
5
Database :
Academic Search Index
Journal :
Pharmaceutical Chemistry Journal
Publication Type :
Academic Journal
Accession number :
132093398
Full Text :
https://doi.org/10.1007/s11094-018-1830-5