ВІДНОСНА РАДІОЧУТЛИВІСТЬ МУТАНТА ARABIDOPSIS THALIANA Atmsh2 SALK_002708 У ДІАПАЗОНІ СУБЛЕТАЛЬНИХ ДОЗ ОПРОМІНЕННЯ РАДІАЦІЄЮ

Effective repair of radiation-induced DNA lesions is an important factor in the radioresistance of plants. Taking into account the role of the DNA mismatch repair (MMR) in the systemic reaction of plants to the action of sublethal doses of ionizing radiation has not yet been sufficiently clear enough. The study of the effect of low LET ionizing radiation in doses up to 21 Gy had been performed, including measurement of the biomass accumulation in Arabidopsis thaliana Atmsh2-/- plants, defective in one of the key components of MMR-repair, MSH2 protein. It has been established that the relative radiosensitivity of Atmsh2 SALK_002708 mutants to the action of sublethal doses of radiation depends on the dose and mode of irradiation. Changes in the radiosensitivity of mutant plants at different doses and due to the fractionation of the dose can be related to the radiation-induced transcriptional response of genes, coding DNA repair proteins, which compensate the lack of MMR-repair or along with MSH2 participate in the mutagenic pathways of DNA repair. [ABSTRACT FROM AUTHOR]