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From a Sequential Chemo-Enzymatic Approach to a Continuous Process for HMF Production from Glucose.
- Source :
-
Catalysts (2073-4344) . Aug2018, Vol. 8 Issue 8, p335. 20p. - Publication Year :
- 2018
-
Abstract
- Notably available from the cellulose contained in lignocellulosic biomass, glucose is a highly attractive substrate for eco-efficient processes towards high-value chemicals. A recent strategy for biomass valorization consists on combining biocatalysis and chemocatalysis to realise the so-called chemo-enzymatic or hybrid catalysis. Optimisation of the glucose conversion to 5-hydroxymethylfurfural (HMF) is the object of many research efforts. HMF can be produced by chemo-catalyzed fructose dehydration, while fructose can be selectively obtained from enzymatic glucose isomerization. Despite recent advances in HMF production, a fully integrated efficient process remains to be demonstrated. Our innovative approach consists on a continuous process involving enzymatic glucose isomerization, selective arylboronic-acid mediated fructose complexation/transportation, and chemical fructose dehydration to HMF. We designed a novel reactor based on two aqueous phases dynamically connected via an organic liquid membrane, which enabled substantial enhancement of glucose conversion (70%) while avoiding intermediate separation steps. Furthermore, in the as-combined steps, the use of an immobilized glucose isomerase and an acidic resin facilitates catalyst recycling. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GLUCOSE
*BIOMASS
*CATALYSIS
Subjects
Details
- Language :
- English
- ISSN :
- 20734344
- Volume :
- 8
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Catalysts (2073-4344)
- Publication Type :
- Academic Journal
- Accession number :
- 131972184
- Full Text :
- https://doi.org/10.3390/catal8080335