Novel bionanocellulose based membrane protected with covalently bounded thin silicone layer as promising wound dressing material.

Graphical abstract Highlights • Novel bionanocellulose blend with covalently bounded silicone layer was developed. • Silicone modified blend exhibits lower tendency to swell compared to pure material. • Developed silicone layers extended the drying time of bionanocellulose membranes. • The silicone covered membranes are promising materials for new wound dressing. Abstract Modification of membrane surface fabricated from bionanocellulose (BNC) carboxymethylcellulose (CMC) blend (BNC-CMC) with covalently bounded silicone layer was carried out in view of developing the novel, moist wound dressing material. The procedure was initiated with the reaction of aminopropyltriethoxysilane (APS) with carboxymethyl groups of CMC resulting with amide bound formation. The thickness of the silicone layer was further increased in the base-catalyzed polycondensation of silicone precursors: vinyltriethoxysilane (VES) or allyltrimethoxysilane (ATMS) initiated by N -(3-dimethylaminopropyl)- N ′-ethylcarbodiimide hydrochloride (EDC). Surface modification was confirmed using various physicochemical methods such as FTIR, SEM, XPS and contact angle measurements. Swelling and drying tests confirmed that silicone-modified materials have considerable better water storage properties than the pristine BNC-CMC nanocomposite. The fabricated silicone modified BNC-CMC membranes are promising materials for wound dressing ensuring improved hydrobalance as the protective layer slows the evaporation of water. [ABSTRACT FROM AUTHOR]