Analysis of results after the implementation of fast recovery protocols in hepatopancreatobiliary surgery.

Background: Hepatopancreatobiliary surgery (HPB) has been able to reducemorbidity and mortality over the past 30 years, as a result of technological breakthroughs, high-volume centers, and the implementation of multidisciplinary groups with fast recovery protocols. Objective: To compare the impact of implementing fast recovery guidelines in patients undergoing HPB surgery. Methods: We conducted an observational retrospective study collecting medical records of patients undergoing HPB surgery from July 2012 to January 2017. An analysis was done of the demographic data, frequent diagnoses, fluid therapy, need for transfusions, length of hospital stay, need for reintervention, and 30-day mortality. Two groups were identified: group A (July 2012-December 2014) and group B (January 2015-January 2017) in which fast recovery protocols were implemented. Results: A total of 364 patients were included, 145 in group A and 219 in group B. The most frequent diagnoses were pancreatic cancer, liver metastasis, cholangiocarcinoma, and bile duct injury. Bleeding was less than 600mL (OR=12,88, CI 95%(5,31-31,23)), the transfusion requirements dropped (OR=0.16; 95% CI: 0.068-0.418), and fluid therapy was below 5000mL in group B (OR=4.23; 95% CI: 1.76-10.11). Length of hospital stay was 3 days (interquartile range 2-5; p<0.001), and mortality at 30 days was lower in group B (p=0.012). Conclusion: The implementation of fast recovery protocols showed a decrease in intraoperative bleeding, intravenous fluids therapy, length of hospital stay, and 30-day mortality. [ABSTRACT FROM AUTHOR]