Photothermal effect of Ag nanoparticles deposited over poly(amidoamine) grafted carbon nanotubes.

This paper illustrates the potential of Ag nanoparticles based nanocomposites to use as effective agents in photothermal therapy apart from their traditional employment as antimicrobial materials. Herein an Near-Infrared active photothermal agent was fabricated by deposition of Ag nanoparticles over aromatic poly(amidoamine) grafted carbon nanotubes. Thus prepared CNTs-PAMAM-Ag possessed strong photothermal effect under exposure to 980 nm laser system and prominent photothermal stability. The photothermal conversion efficiency of CNTs-PAMAM-Ag was found to be higher than readily used Au and CuS based photothermal agents. The photothermal effect of CNTs-PAMAM-Ag was substantial in presence of 980 nm laser compared to 808 nm laser and a linear dependence of photothermal effect on its concentration was identified. The maximum temperature attained by CNTs-PAMAM-Ag during assessment of its photothermal effect was about 66.0 °C, which is significantly higher than the survival temperature level of cancer cells. So CNTs-PAMAM-Ag could be a promising photothermal agent to apply in future photothermal hyperthermia therapy to treat cancer. Moreover CNTs-PAMAM-Ag can synchronous trigger by a single wavelength (980 nm) laser system, so it could simplify the future therapeutic process. [ABSTRACT FROM AUTHOR]