Incorporation of the bioactive moiety of leinamycin into thymidine

Authors :: Szilágyi, Ákos
Pelyvás, István F.
Majercsik, Orsolya
Herczegh, Pál
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. May2004, Vol. 45 Issue 22, p4307-4309. 3p.
Publication Year :: 2004
Abstract: A simple synthesis of 1,2-dithiolan-3-ones from α,β-unsaturated thiophenyl esters has been elaborated. With the aim of introducing the biologically active 1,2-dithiolan-3-one-1-oxide moiety of leinamycin into a nucleoside, the method was successfully applied to thymidine-5′-aldehyde. [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 45
Issue :: 22
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 13064748
Full Text :: https://doi.org/10.1016/j.tetlet.2004.04.011