Highly Enantioselective Kinetic Resolution of Michael Adducts through N‐Heterocyclic Carbene Catalysis: An Efficient Asymmetric Route to Cyclohexenes.

Abstract: A highly efficient strategy for the kinetic resolution of Michael adducts was realized using a chiral N‐heterocyclic carbene catalyst. The kinetic resolution provides a new convenient route to single diastereomers of cyclohexenes and Michael adducts in good yields with high enantiomeric excesses (up to 99 % ee with a selectivity factor of up to 458). This “two flies with one swat” concept allows the synthesis of these two synthetically valuable compound classes at the same time by a single transformation. [ABSTRACT FROM AUTHOR]