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Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials.
- Source :
-
BioMed Research International . 7/5/2018, Vol. 2018, p1-12. 12p. - Publication Year :
- 2018
-
Abstract
- Aim. To investigate whether vitamin C is effective in the treatment of the common cold. Method. After systematically searching the National Library of Medicine (PubMed), Cochrane Library, Elsevier, China National Knowledge Infrastructure (CNKI), VIP databases, and WANFANG databases, 9 randomized placebo-controlled trials were included in our meta-analysis in RevMan 5.3 software, all of which were in English. Results. In the evaluation of vitamin C, administration of extra therapeutic doses at the onset of cold despite routine supplementation was found to help reduce its duration (mean difference (MD) = -0.56, 95% confidence interval (CI) [-1.03, -0.10], and P = 0.02), shorten the time of confinement indoors (MD = -0.41, 95% CI [-0.62, -0.19], and P = 0.0002), and relieve the symptoms associated with it, including chest pain (MD = -0.40, 95% CI [-0.77, -0.03], and P = 0.03), fever (MD = -0.45, 95% CI [-0.78, -0.11], and P = 0.009), and chills (MD = -0.36, 95% CI [-0.65, -0.07], and P = 0.01). Conclusions. Extra doses of vitamin C could benefit some patients who contract the common cold despite taking daily vitamin C supplements. [ABSTRACT FROM AUTHOR]
- Subjects :
- *THERAPEUTIC use of vitamin C
*AGE factors in disease
*CHEST pain
*COMMON cold
*CONFIDENCE intervals
*DIETARY supplements
*FEVER
*MEDICAL databases
*INFORMATION storage & retrieval systems
*MEDLINE
*META-analysis
*ONLINE information services
*VITAMIN C
*SYSTEMATIC reviews
*RANDOMIZED controlled trials
*TREATMENT effectiveness
*SHIVERING
*DISEASE duration
*DATA analysis software
*SYMPTOMS
Subjects
Details
- Language :
- English
- ISSN :
- 23146133
- Volume :
- 2018
- Database :
- Academic Search Index
- Journal :
- BioMed Research International
- Publication Type :
- Academic Journal
- Accession number :
- 130506036
- Full Text :
- https://doi.org/10.1155/2018/1837634