Measurement of Human Immunodeficiency Virus p24 Antigen in Human Cerebrospinal Fluid With Digital Enzyme-Linked Immunosorbent Assay and Association With Decreased Neuropsychological Performance.

Authors :: Anderson, Albert M
Tyor, William R
Mulligan, Mark J
Waldrop-Valverde, Drenna
Lennox, Jeffrey L
Letendre, Scott L
Source :: Clinical Infectious Diseases. Jul2018, Vol. 67 Issue 1, p137-140. 4p.
Publication Year :: 2018
Abstract: New tools are needed to understand human immunodeficiency virus central nervous system involvement. Testing 15 cerebrospinal fluid (CSF) samples for p24 antigen, using a high-sensitivity assay, we found a strong correlation trend between CSF p24 concentration and worse neuropsychological performance. [ABSTRACT FROM AUTHOR]

Subjects :: *CENTRAL nervous system
*ENZYME-linked immunosorbent assay
*HIV
*IMMUNOASSAY
*NEUROPSYCHOLOGICAL tests
*VIRAL antigens

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