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Analysis of Solanum Americanum Mill. by Ultrafast Liquid Chromatography with Diode Array and Time-Of-flight Mass Spectrometry Detection with Evaluation of Anti-Inflammatory Properties in Rodent Models.
- Source :
-
Analytical Letters . 2018, Vol. 51 Issue 13, p1973-1985. 13p. 1 Chart, 5 Graphs. - Publication Year :
- 2018
-
Abstract
- Solanum americanum Mill. has been traditionally used for the treatment of fever, stomachache, skin diseases, gynecological disorders, and different kinds of inflammation. This study evaluated the anti-inflammatory response of different extracts obtained from ripe fruits of S. americanum Mill., in experimental models and evaluated them qualitatively using ultrafast liquid chromatography with diode array and time-of-flight mass spectrometry (UFLC-DAD/TOF-MS). The inflammatory response of four extracts of ripe fruits was evaluated for the systemic and topical anti-inflammatory activities. The compounds in each extract were identified using UFLC-DAD-TOF/MS. A total of 34 compounds was identified in the four extracts. The best results were obtained in compounds from the aqueous and chloroform extracts. This study demonstrated a significant anti-inflammatory activity for the compounds present in fruit of S. americanum Mill. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00032719
- Volume :
- 51
- Issue :
- 13
- Database :
- Academic Search Index
- Journal :
- Analytical Letters
- Publication Type :
- Academic Journal
- Accession number :
- 129976465
- Full Text :
- https://doi.org/10.1080/00032719.2017.1399413