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Analysis of Solanum Americanum Mill. by Ultrafast Liquid Chromatography with Diode Array and Time-Of-flight Mass Spectrometry Detection with Evaluation of Anti-Inflammatory Properties in Rodent Models.

Authors :
Vagula, Julianna M.
Rocha, Bruno A.
Silva, Alexandre R.
Narain, Narendra
Bersani-Amado, Ciomar A.
Junior, Oscar O. S.
Visentainer, JesuĂ­ V.
Source :
Analytical Letters. 2018, Vol. 51 Issue 13, p1973-1985. 13p. 1 Chart, 5 Graphs.
Publication Year :
2018

Abstract

Solanum americanum Mill. has been traditionally used for the treatment of fever, stomachache, skin diseases, gynecological disorders, and different kinds of inflammation. This study evaluated the anti-inflammatory response of different extracts obtained from ripe fruits of S. americanum Mill., in experimental models and evaluated them qualitatively using ultrafast liquid chromatography with diode array and time-of-flight mass spectrometry (UFLC-DAD/TOF-MS). The inflammatory response of four extracts of ripe fruits was evaluated for the systemic and topical anti-inflammatory activities. The compounds in each extract were identified using UFLC-DAD-TOF/MS. A total of 34 compounds was identified in the four extracts. The best results were obtained in compounds from the aqueous and chloroform extracts. This study demonstrated a significant anti-inflammatory activity for the compounds present in fruit of S. americanum Mill. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00032719
Volume :
51
Issue :
13
Database :
Academic Search Index
Journal :
Analytical Letters
Publication Type :
Academic Journal
Accession number :
129976465
Full Text :
https://doi.org/10.1080/00032719.2017.1399413