不同糖尿病风险评分在体检人群中应用的 效果评价.

Objective To explore the effect of different diabetic risk score in screening for diabetes mellitus in the health check-up population, and to analyze the risk factors of abnormal glucose metabolism. Methods Diabetes risk scores screening was conducted in people who participated physical examination in Medical Examination Center of Beijing Hospital in 2015. The area under the curve (AUC) of the receiver operating characteristic curve was used to reflect the accuracy of the screening method. The relevant risk factors of abnormal glucose metabolism were used by multivariate logistic regression analysis. Results (1) The AUC of screening for diabetes by Chinese diabetes risk score (C-DRs) was 0.83 [95% confidence interval (CI) 0.811-0.843], and the best cut-point value was 26.5. The sensitivity was 83.48%, the specificity was 61.45%, and the Younden index was 0.45 (P<0.05). (2) Age [odds ratio (OR)=2.646, 95%CI: 1.707-4.101], family history of diabetes (OR=13.103, 95%CI: 6.076-28.259), BMI≥25 kg/m2 (OR=2.400, 95%CI: 1.609-2.580), male abdominal circumference≥90 cm (OR=3.869, 95% CI: 1.687-8.872), female abdominal circumference≥85 cm (OR=1.787, 95%CI: 1.183-2.699), hypertention (OR=7.812, 95%CI: 1.560-39.113), high triglyceride (TG) (≥1.7 mmol/L) (OR=1.751, 95%CI: 1.138-2.696), smoking history (OR=3.974, 95% CI: 2.085-7.474), less than 150 min moderate physical activity per week (OR=10.446, 95% CI: 5.304-20.574), more than 100 g carbohydrates per meal (OR=58.581, 95%CI: 24.899-137.826) were risk factors for abnormal glucose metabolism (all P<0.05). (3) In combination with the above risk factors used to screen for diabetes, the AUC was 0.88 (95%CI: 0.862-0.890), the best cut-point value was 31.5, the sensitivity was 88.60%, the specificity 68.68%, the Jordanian index was 0.57 (P<0.05). Conclusions C-DRs is more suitable for diabetes screening in Chinese population. Combined with the factors as: less than 150 min moderate physical activity per week, more than 100 g carbohydrates per meal, smoking history, and high triglycerides, can improve the sensitivity and specificity of screening for diabetes mellitus. [ABSTRACT FROM AUTHOR]