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Sarinfacetamides A and B, Nitrogenous Diterpenoids with Tricyclo[6.3.1.01,5]dodecane Scaffold from the South China Sea Soft Coral Sarcophyton infundibuliforme.
- Source :
-
Organic Letters . 5/4/2018, Vol. 20 Issue 9, p2637-2640. 4p. - Publication Year :
- 2018
-
Abstract
- Two novel nitrogenous diterpenoids, sarinfacetamides A (1) and B (2), featuring an uncommon tricyclo[6.3.1.01,5]dodecane scaffold, and a known related diterpene (3) were isolated from the South China Sea soft coral Sarcophyton infundibuliforme. Their structures, including the absolute configuration of 1, were established by extensive spectroscopic analysis and TDDFT-ECD calculation. Compounds 1 and 3 exhibited interesting promotion effects on the ConA-induced T lymphocyte proliferation. A plausible biosynthetic pathway for 1 and 2 was also proposed. [ABSTRACT FROM AUTHOR]
- Subjects :
- *AMIDES
*DITERPENES
*ALCYONACEA
*ALCYONIIDAE
*BIOSYNTHESIS
*SPECTRUM analysis
Subjects
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 20
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 129578922
- Full Text :
- https://doi.org/10.1021/acs.orglett.8b00842