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Autoxidation Photoredox Catalysis for the Synthesis of 2-Phosphinoylindoles.
- Source :
-
Organic Letters . 4/20/2018, Vol. 20 Issue 8, p2382-2385. 4p. - Publication Year :
- 2018
-
Abstract
- A new approach to the synthesis of 2-phosphinoylindoles through photoredox catalysis without external oxidants has been developed. Promoted by a ruthenium photoredox catalyst, a broad scope of 2-phosphinoylindoles can be synthesized through phosphinoylation/cyclization of diphenylphosphine oxide at room temperature under irradiation without external oxidants. The estrone skeleton isocyan is also an amenable substrate for this cyclization, yielding a molecule that has potential medicinal applications. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 15237060
- Volume :
- 20
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Organic Letters
- Publication Type :
- Academic Journal
- Accession number :
- 129347785
- Full Text :
- https://doi.org/10.1021/acs.orglett.8b00722