Nano-perovskite decorated carbon nanotubes composite for ultrasensitive determination of a cardio-stimulator drug.

In this work, a new electrochemical sensor was fabricated based on Sr 2 PdO 3 nano-perovskite manually mixed with carbon nanotubes (CNTs) and casted on glassy carbon (GC) electrode surface; GC/(CNTs-Sr 2 PdO 3 ). Enhanced sensitivity, selectivity, stability and electron transfer kinetics were realized by the application of nano-perovskite modified carbon nanotubes composite for determination of dobutamine (DB). The proposed sensor showed high electro-catalytic activity in the linear dynamic range of 0.03 μmol L −1 to 50 μmol L −1 with sensitivity of 20.91 μA/μmol L −1 , detection limit of 0.012 nmol L −1 and a quantification limit of 0.04 nmol L −1 . The proposed method was successfully applied for DB detection in blood serum samples with good recovery results. The sensor showed anti-interfering ability in presence of common interferences as ascorbic acid, uric acid, acetaminophen, serotonin and morphine. [ABSTRACT FROM AUTHOR]