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Stylet slow-pull versus standard suction for endoscopic ultrasound-guided fine-needle aspiration of solid pancreatic lesions: a multicenter randomized trial.
- Source :
-
Endoscopy . 2018, Vol. 50 Issue 5, p497-504. 8p. - Publication Year :
- 2018
-
Abstract
- <bold>Background and Study Aim: </bold>Standard endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) procedures involve use of no-suction or suction aspiration techniques. A new aspiration method, the stylet slow-pull technique, involves slow withdrawal of the needle stylet to create minimum negative pressure. The aim of this study was to compare the sensitivity of EUS-FNA using stylet slow-pull or suction techniques for malignant solid pancreatic lesions using a standard 22-gauge needle.<bold>Patients and Methods: </bold>Consecutive patients presenting for EUS-FNA of pancreatic mass lesions were randomized to the stylet slow-pull or suction techniques using a 22-gauge needle. Both techniques were standardized for each pass until an adequate specimen was obtained, as determined by rapid on-site cytology examination. Patients were crossed over to the alternative technique after four nondiagnostic passes.<bold>Results: </bold>Of 147 patients screened, 121 (mean age 64 ± 13.8 years) met inclusion criteria and were randomized to the stylet slow-pull technique (n = 61) or the suction technique (n = 60). Technical success rates were 96.7 % and 98.3 % in the slow-pull and suction groups, respectively (P > 0.99). The sensitivity for malignancy of EUS-FNA was 82 % in the slow-pull group and 69 % in the suction group (P = 0.10). The first-pass diagnostic rate (42.6 % vs. 38.3 %; P = 0.71), acquisition of core tissue (60.6 % vs. 46.7 %; P = 0.14), and the median (range) number of passes to diagnosis (2 1 2 3 vs. 1 1 2; P = 0.71) were similar in the slow-pull and suction groups, respectively.<bold>Conclusions: </bold>The stylet slow-pull and suction techniques both offered high and comparable diagnostic sensitivity with a mean of 2 passes required for diagnosis of solid pancreatic lesions. The endosonographer may choose either technique during FNA. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ENDOSCOPIC ultrasonography
*NEEDLE biopsy
*PANCREATIC cancer
Subjects
Details
- Language :
- English
- ISSN :
- 0013726X
- Volume :
- 50
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Endoscopy
- Publication Type :
- Academic Journal
- Accession number :
- 129317565
- Full Text :
- https://doi.org/10.1055/s-0043-122381