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Repopulating retinal microglia restore endogenous organization and function under CX3CL1-CX3CR1 regulation.

Authors :
Yikui Zhang
Lian Zhao
Xu Wang
Wenxin Ma
Lazere, Adam
Hao-hua Qian
Jun Zhang
Abu-Asab, Mones
Fariss, Robert N.
Roger, Jerome E.
Wong, Wai T.
Source :
Science Advances. Mar2018, Vol. 4 Issue 3, p1-14. 14p.
Publication Year :
2018

Abstract

The article offers information on a study which examined microglial homeostasis and repopulation in adult mouse retina. It mentions that a cell-fate mapping technique was performed. It shows that the repopulation of retinal microglia restores function and endogenous organization under CX3CL1-CX3CR1 signaling regulation.

Details

Language :
English
ISSN :
23752548
Volume :
4
Issue :
3
Database :
Academic Search Index
Journal :
Science Advances
Publication Type :
Academic Journal
Accession number :
128897812
Full Text :
https://doi.org/10.1126/sciadv.aap8492