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Cryogen Spray Cooling during Nd:YAG Laser Treatment of Hemangiomas.
- Source :
-
Dermatologic Surgery . Aug1997, Vol. 23 Issue 8, p635-641. 7p. - Publication Year :
- 1997
-
Abstract
- BACKGROUND. <em>Successful laser treatment of hemangiomas requires selective photothermal destruction of dilated cutaneous vessels without damaging the overlying epidermis. Delivering a short cryogen spurt, on the order of milliseconds, has been shown to result in localized cooling of the superficial skin structures during laser irradiation</em>. OBJECTIVE.<em>The purpose of this study was to examine the effectiveness of cryogen spray cooling (CSC) in protecting superficial tissue structures during continuous Nd:YAG laser irradiation of an in vivo model hemangioma.</em> METHODS. <em>The highly vascularized chicken comb was selected as the animal model for hemangioma. The ND:YAG laser irradiation ranged from 2.6 to 35.1 1/mm². A feedback system utilizing infrared rediometry monitored the comb surface temperature and controlled delivery time to the cryogen spurt. When comb surface temperature during laser irradiation reached 36-42°C, a 30-100 msec cryogen spurt was delivered. Animals were euthanized 1 hour to 21 days following each experiment. Gross and histologic analyses were performed.</em> RESULTS. <em>Nd:YAG laser irradiation resulted in deep (up to 6.1 mm) tissue photocoagulation, which CSC preserved the overlying epidermis and papillary dermis</em>. CONCLUSION. <em>The results demonstrate that CSC is effective in protecting the epidermis and papillary dermis and papillary dermis, while achieving deep tissue photocoagulation during ND:YAG laser irradiation. Further pilot studies in humans appear warranted</em>. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEMANGIOMAS
*LASERS
*THERAPEUTICS
*CRYOSURGERY
*IRRADIATION
*EPIDERMIS
*HISTOLOGY
Subjects
Details
- Language :
- English
- ISSN :
- 10760512
- Volume :
- 23
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Dermatologic Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 12884137
- Full Text :
- https://doi.org/10.1111/j.1524-4725.1997.tb00381.x