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Diagnosis and Management of Immune Checkpoint Inhibitor–related Toxicities in Ovarian Cancer: A Series of Case Vignettes.
- Source :
-
Clinical Therapeutics . Mar2018, Vol. 40 Issue 3, p389-394. 6p. - Publication Year :
- 2018
-
Abstract
- Use of immune checkpoint inhibitors targeting cytotoxic T-lymphocyte-associated antigen 4 and programmed cell death protein 1 have led to improved survival outcomes for advanced solid-tumor malignancies. This report helps the reader gain a better understanding of adverse events in patients with ovarian cancer on checkpoint inhibitor therapy. We describe 3 hypothetical case vignettes of patients with gynecologic cancer on checkpoint inhibitor immunotherapy and discuss common immune-related adverse events. The typical presentation and onset of immune-related events are different from those associated with conventional chemotherapy. This report highlights the importance of early recognition and management of these events. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01492918
- Volume :
- 40
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Clinical Therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 128518187
- Full Text :
- https://doi.org/10.1016/j.clinthera.2018.02.011