Coagulation Profile in Iron Deficiency Anaemia in Antenatal Age Group.

Background: The high frequency of iron deficiency anaemia in the developing world has substantial health and economic costs. Women in developing countries are always in a state of precarious iron balance during their reproductive years. Their iron stores are not well developed because of poor nutritional intake, recurrent infections, menstrual blood loss, and repeated pregnancies. Gender discrimination in a country like India resulting in girls lacking access to a balanced diet, adequate health care and proper education. Aim: 1) To study the coagulation profile in iron deficiency anemia in ante-natal patients. 2) To compare changes in coagulation profile of control without iron deficiency anemia with iron deficiency anemia patients. Material & Method: From February 2015 to July 2016 was carried out in the Department of Pathology, Department of Obstetrics and Gynecology, Saraswathi Institute of Medical Sciences and associated Hospital, Hapur, Uttar Pradesh, India, Which included 200 patients of anemia presenting in obs and gyne department. Results: Out of two hundred pregnant females mean age was 29.84+-7.87with reference range between 19-45. Fifty % of total cases had normal Hb 23.5% had mild anemia where as 11.5% had severe anemia. Mean PT was 11.80+-2.99 with a reference range of 3-21. Mean APTT was 30.35 +-5.08 with reference range of 2.9-40. Mean ferritin was 52.86 +/- 59.28 with reference range of 1-174. Conclusion: Iron plays a role in alteration of coagulation profile in iron deficiency anemic pregnancies. Changes in RBC indices are more pronounced in iron deficiency anemia. [ABSTRACT FROM AUTHOR]