Synthesis of Methyl-Substituted Derivatives of 5-Hydroxy-6-methyluracil.

5-Hydroxy-3,6-dimethyluracil, 5-methoxy-1,3,6-trimethyluracil, earlier unknown 5-methoxy-6- methyluracil, 5-methoxy-1,6-dimethyluracil, and 5-methoxy-3,6-dimethyluracil have been synthesized via alkylation of 5-hydroxy-6-methyluracil with dimethylsulfate in aqueous-alkaline media. The obtained compounds have been identified using ¹H, 13C, and 15N NMR spectroscopy. [ABSTRACT FROM AUTHOR]