Facile and efficient preparation of α-halomethyl ketones from α-diazo ketones catalyzed by iron(III) halides and silica gel.

Authors :: Shi, Xinxia
Zhang, Lingqiong
Yang, Pengfei
Sun, Han
Zhang, Yilan
Xie, Chunsong
Ou-yang, Zhen
Wang, Min
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Mar2018, Vol. 59 Issue 13, p1200-1203. 4p.
Publication Year :: 2018
Abstract: An efficient and mild method for the synthesis of α-halomethyl ketones from α-diazo ketones was developed using ferric chloride or bromide as the halogen source and silica gel as the hydrogen source, with good to excellent yields. [ABSTRACT FROM AUTHOR]

Subjects :: *FERRIC chloride
*SILICA gel
*COLLOIDS
*NEODYMIUM
*VILSMEIER reagents

Language :: English
ISSN :: 00404039
Volume :: 59
Issue :: 13
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 128286759
Full Text :: https://doi.org/10.1016/j.tetlet.2018.02.024

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