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EPS8 signaling as a therapeutic target in oral cancer.

Authors :
Yeudall, A.
Patel, V.
Source :
Oral Diseases. Mar2018, Vol. 24 Issue 1/2, p128-131. 4p.
Publication Year :
2018

Abstract

The article discusses the role of epidermal growth factor receptor (EGFR) pathway substrate 8 (EPS8) as treatment for patient with oral cancer. It mentions that EPS8 influence a range of normal biological processes such as trafficking of the EGFR, regulation of actin dynamics and cellular proliferation.

Subjects

Subjects :
*THERAPEUTIC use of monoclonal antibodies
*PROTEIN-tyrosine kinase inhibitors
*CELL proliferation
*CANCER chemotherapy
*CELLULAR signal transduction
*DRUG delivery systems
*EPIDERMAL growth factor
*GENE expression
*GROWTH factors
*MOUTH tumors
*PROTEIN-tyrosine kinases
*MATRIX metalloproteinases
*CHEMICAL inhibitors
*THERAPEUTICS

Details

Language :
English
ISSN :
1354523X
Volume :
24
Issue :
1/2
Database :
Academic Search Index
Journal :
Oral Diseases
Publication Type :
Academic Journal
Accession number :
128210121
Full Text :
https://doi.org/10.1111/odi.12766
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