Back to Search
Start Over
Bioactive polyoxygenated seco-cyclohexenes from Artabotrys hongkongensis.
- Source :
-
Bioorganic Chemistry . Feb2018, Vol. 76, p386-391. 6p. - Publication Year :
- 2018
-
Abstract
- Six new polyoxygenated seco-cyclohexenes, artahongkongenes A–F ( 1–6 ), together with six known analogues ( 7–12 ) were isolated from the stems and leaves of Artabotrys hongkongensis . Their structures were elucidated by extensive spectroscopic methods. All new compounds were evaluated for their cytotoxicities against five human cancer cell lines: HL-60, SMMC-7721, A-549, MCF-7 and SW480 in vitro . New seco-cyclohexenes 1–6 showed significant inhibitory effects against various human cancer cell lines with IC 50 values ranging from 0.26 to 16.58 μM. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00452068
- Volume :
- 76
- Database :
- Academic Search Index
- Journal :
- Bioorganic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 128046413
- Full Text :
- https://doi.org/10.1016/j.bioorg.2017.12.011