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Four new compounds from the roots of Euphorbia ebracteolata and their inhibitory effect on LPS-induced NO production.
- Source :
-
Fitoterapia . Mar2018, Vol. 125, p235-239. 5p. - Publication Year :
- 2018
-
Abstract
- Three new diterpenoids, ebractenoids O ~ Q ( 1 – 3 ), and a new phenolic glucoside, γ -pyrone-3- O - β - d -(6-galloyl)-glucopyranoside ( 4 ), together with 6 known compounds, were isolated from the 95% ethanol extract of the roots of Euphorbia ebracteolata , and their structures were elucidated on the basis of spectroscopic data. The absolute configurations of 1 – 3 were determined by electronic circular dichroism (ECD) calculations. The inhibitory effects of all the isolates with exception of compounds 8 and 10 on the NO production in lipopolysaccharide (LPS)-induced macrophages were evaluated. All of them exhibited significant inhibitory activity. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0367326X
- Volume :
- 125
- Database :
- Academic Search Index
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 127871956
- Full Text :
- https://doi.org/10.1016/j.fitote.2017.12.006