A low‐grade astrocytoma in a sixteen‐year‐old boy with a 7q11.22 deletion.

Authors :: van Kampen, Francoise S.
Doornbos, Marianne E.
van Rijn, Monique A.
den Bever, Yolande
Source :: Clinical Case Reports. Feb2018, Vol. 6 Issue 2, p274-277. 4p.
Publication Year :: 2018
Abstract: Key Clinical Message: We report a patient with developmental delay due to germline AUTS2 mutation who developed a low‐grade astrocytoma. While the contribution of this mutation to the pathogenesis of the tumor is not known at this time, a role of AUTS2 in deregulation of PRC1 can be a part in tumorigenesis of a brain tumor. [ABSTRACT FROM AUTHOR]