经腹超声引导聚桂醇联合射频消融术治疗子宫肌瘤的临床疗效及对患者 血清E2、LH、FSH水平的影响

Objective: To study the curative efficacy of transabdominal ultrasound-guided Lauromacrogol combined with radiofrequency ablation hi the treatment of fibroid and its effects on the serum estradiol (E2), luteinizing hormone (LH). follicle stimulating hormone (FSH) levels. Methods: 90 patients of fibroid who were treated from June 2014 to June 2015 hi our hospital were selected as the research objects. According to random number table,those patients were divided hito the observation group (n=45) and the control group (n=45). Both groups were routinely examined before operation, the control group was treated with transabdomhial ultrasound radiofrequency ablation, while the observation group was treated with transabdomhial ultrasound-guided percutaneous radiofrequency ablation combined with radiofrequency ablation. Then visual analogue scale (VAS). menstrual volume, uterine fibroid volume, uterine volume. E2. LH. FSH levels, myoma symptoms and quality of life score, curative effect were compared between two groups. Results: After treatment, the total effective rate of observation group was significantly higher than that of the control group [95.55%(43/45)vs75.55%(34/45)] (P< 0.05): the VAS score, menstrual volume were significantly lower than those of the control group [ (1.05± 0.23)score vs. (3.62± 0.50)score. (192.35± 22.10)mL 1 vs. (236.541 24.57)mL](P< 0.05): The myoma volume, uterine volume were significantly lower than those of the control group[(32.131 13.20)cm3 vs(40.81± 14.11 )cm3. (101.931 9.89)cm3vs(l 18.361 11.20) cm3](P< 0.05): the serum E2. LH. FSH levels were significantly lower than those before treatment, but there was no difference between the two groups (P>0.05); the fibroid symptoms score was significantly lower than that of the control group [(4.501 1.02)score vs. (10.341 2.21)score] (P< 0.05). the quality of life score was significantly higher than that of the control group [(95.361 14.29)score vs. (80.841 14.06)score](P< 0.05). Conclusion: Transabdominal ultrasound-guided lauromacrogol combined with radiofrequency ablation could enhance the efficacy of fibroid, which might be related to the decrease of serumlevels of E2, LH, and FSH. [ABSTRACT FROM AUTHOR]