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The role of glutamate and its receptors in central nervous system in stress-induced hyperalgesia.
- Source :
-
International Journal of Neuroscience . Mar2018, Vol. 128 Issue 3, p283-290. 8p. - Publication Year :
- 2018
-
Abstract
- Purpose:To explore the potential mechanisms of glutamate and its receptors in stress-induced hyperalgesia. Materials and methods:The stress-induced hyperalgesia, glutamate and its receptors are listed as key items in the pubmed database and the related articles are searched. Results:Glutamate level is increased under stress and associated with stress-induced hyperalgesia. Moreover, the role of glutamate in stress-induced hyperalgesia depends on its subtypes of its receptors. Conclusions:Increased glutamate during stress connect with ionotropic glutamate receptors can prompt hyperalgesia, but connect with metabotropic glutamate receptors can inhibit hyperalgesia. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00207454
- Volume :
- 128
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- International Journal of Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 127094956
- Full Text :
- https://doi.org/10.1080/00207454.2017.1387112