ATIVIDADE ANTIMICROBIANA DO EXTRATO HIDROALCÓOLICO DE FICUS CARICA E POLYGALA SPECTABILIS.

The objective was to evaluate the antimicrobial effectiveness of different formulations of herbal candidates, produced from leafs of caamembeca (Polygala spectabilis - EFC) and common fig (Ficus carica - EFF). Extracts were produced with 30 days of percolation at 4°C and lyophilized; subsequently they were used to perform the phytochemical march, toxicity test and antioxidant test. The antibacterial bioassay was performed against Clostridium perfringens, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus using dilution with exponential concentrations (20 µg.ml-1-2560 µg.ml-1) of the extracts. Several compounds with antimicrobial properties were determined in phytochemical analysis. The antioxidant activity measured at 640 ug/ml, compared to the ascorbic acid was 68.4% for the EFC while for the EFF was 89.9%. The EFF was efficacious in different concentrations, against all bacteria tested, with the minimum bacterial concentration (MBC) of 1280; 2560; 1280 e 320 µg/ml, to C. perfringens, E. coli, P. aeruginosa e S. aureus, however the EFC only acted against S. aureus, with 2560 ug/ml MBC. The results of the biochemical tests, along with those found in in vitro tests showed that the EFF may be considered as an antimicrobial candidate. [ABSTRACT FROM AUTHOR]