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New facilities of Biginelli reaction. Synthesis of methyl 6-aryl-5-benzoyl-4-methoxy-2-oxohexahydropyrimidine-4-carboxylates.
- Source :
-
Russian Journal of Organic Chemistry . Nov2017, Vol. 53 Issue 11, p1675-1677. 3p. 3 Diagrams. - Publication Year :
- 2017
-
Abstract
- Three-component reaction of methyl benzoylpyruvate, aromatic aldehyde, and urea in methanol in the presence of sodium bisulfate stops at the stage of the formation of nondehydrated product with a methylated tertiary hydroxy group and results in methyl 6-aryl-5-benzoyl-4-methoxy-2-oxohexahydropyrimidine-4-carboxylates. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CHEMICAL synthesis
*PYRIMIDINES
*CARBOXYLATES
*CHEMICAL reactions
*HYDROXY acids
Subjects
Details
- Language :
- English
- ISSN :
- 10704280
- Volume :
- 53
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Russian Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 126970067
- Full Text :
- https://doi.org/10.1134/S1070428017110100