A photochemical flow reactor for large scale syntheses of aglain and rocaglate natural product analogues.

Herein, we report the development of continuous flow photoreactors for large scale ESIPT-mediated [3+2]-photocycloaddition of 2-( p- methoxyphenyl)-3-hydroxyflavone and cinnamate-derived dipolarophiles. These reactors can be efficiently numbered up to increase throughput two orders of magnitude greater than the corresponding batch reactions. [ABSTRACT FROM AUTHOR]