A retrospective clinicopathological study of lung adenocarcinoma: Total tumor size can predict subtypes and lymph node involvement.

Purpose To analyze the predictive ability of total tumor size in lung adenocarcinoma subtype and lymph node involvement. Materials and methods 1018 patients, ≤ 3 cm tumor, were enrolled. The maximum diameter and other variables of each tumor were measured. Results The optimal cut-off value for total tumor size in differentiating AIS and MIA from IAC was < 1.15 cm, in distinguishing lymph node involvement, it was 1.65 cm. Conclusions Total tumor size could be a reliable predictor of lung adenocarcinoma subtype and lymph node involvement irrespective of ground glass, part solid and solid characteristics. [ABSTRACT FROM AUTHOR]