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Severe pyoderma gangrenosum caused by myelodysplastic syndrome successfully treated with decitabine administered by a noncytotoxic regimen.
- Source :
-
Clinical Case Reports . Dec2017, Vol. 5 Issue 12, p2025-2027. 3p. - Publication Year :
- 2017
-
Abstract
- Key Clinical Message Pyoderma gangrenosum ( PG) is a morbid necrotizing neutrophilic dermatoses for which current treatments are inadequate. Here, we describe the use of a novel noncytotoxic regimen of the deoxycytidine analog decitabine to treat underlying myeloid malignancy causing PG, to thereby produce safe and effective resolution of extensive PG. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DEOXYCYTIDINE
*DECITABINE
*MYELOID metaplasia
*THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 20500904
- Volume :
- 5
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Clinical Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- 126564961
- Full Text :
- https://doi.org/10.1002/ccr3.1221