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Catalytic asymmetric synthesis of Leukotriene B4.

Authors :
Yang, Pengfei
Zhong, Jiangchun
Ji, Kaijie
Yin, Jingwei
Li, Shuoning
Wei, Siyuan
Zhou, Yun
Wang, Lifeng
Wang, Min
Bian, Qinghua
Source :
Tetrahedron: Asymmetry. Nov2017, Vol. 28 Issue 11, p1596-1601. 6p.
Publication Year :
2017

Abstract

Leukotriene B 4 1 was prepared from two chiral synthons 8 and 14 . The chiral secondary alcohols of 8 and 14 were constructed by BINOL/Ti(O i Pr) 4 catalyzed enantioselective alkynylzinc addition to aldehydes. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*CHIRALITY
*CATALYTIC activity
*ASYMMETRY (Chemistry)
*LEUKOTRIENES
*ALDEHYDES

Details

Language :
English
ISSN :
09574166
Volume :
28
Issue :
11
Database :
Academic Search Index
Journal :
Tetrahedron: Asymmetry
Publication Type :
Academic Journal
Accession number :
126559121
Full Text :
https://doi.org/10.1016/j.tetasy.2017.09.013
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