Okuläre Myasthenie.

The varying combination of fluctuating ptosis, diplopia, and fatigability of orbicularis oculi and extraocular eye muscles, but with normally reacting pupils, is typical for ocular myasthenia gravis. Up to 80% of patients will develop generalized myasthenia gravis within two years. Diagnosis is often delayed, because symptoms are often insidious and can readily be confused with many other neuroophthalmologic or neurologic conditions. The common ancillary tests all yield reduced sensitivities in ocular compared to generalized myasthenia gravis, mainly because the eye muscles are not yet accessible for direct diagnostic testing. Rapid diagnosis is important, as efficacious treatment options are available, and because early immunosuppression in ocular myasthenia gravis may lower the risk of generalization. [ABSTRACT FROM AUTHOR]