Different effects of rotigotine and ropinirole on cholinergic transmission in the mouse medial prefrontal cortex.

The article examines the impact of rotigotine and ropinirole on cholinergic transmission in the mouse medial prefrontal cortex. Topics discussed include use of rotigotine and ropinirole for the treatment of Parkinson's disease; analysis of receptor binding profiles of the drugs; and impact of injection of rotigotine in enhancing the Ach release affecting the rotigotine administration on the cholinergic transmission.