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Risk of Non-melanoma Skin Cancer in Patients with Chronic Kidney Disease and its Relationship to Uraemic Pruritus.

Authors :
Chia-Chen WANG
Chao-Hsiun TANG
Siao-Yuan HUANG
Kuan-Chih HUANG
Yuh-Mou SUE
Source :
Acta Dermato-Venereologica. Nov2017, Vol. 97 Issue 10, p1230-1234. 5p.
Publication Year :
2017

Abstract

This study investigated the risk of non-melanoma skin cancer (NMSC) in pre-dialysis patients with chronic kidney disease (CKD) and explored associated risk factors. A population-based cohort of 1,515,858 Taiwanese CKD patients was included. The standardized incidence ratio (SIR) for incident NMSC was determined. Compared with the general population, a 1.14- fold risk of NMSC was found in the CKD cohort. NMSC risk was significant in patients with pre-dialysis stage 5 CKD and anaemia (1.48-fold), and in those with uraemic pruritus after long-term antihistamine treatment (1.38-fold). A higher SIR for NMSC was found in younger patients with CKD (age < 70 years, 1.34-fold; age 20-39 years, 1.63-fold), stage 5 CKD with anaemia (age < 70 years, 2.09-fold), and uraemic pruritus (age <70 years, 2.22-fold). Pre-dialysis patients with CKD are at higher risk of NMSC, especially those with advanced-stage CKD, and those with uraemic pruritus. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00015555
Volume :
97
Issue :
10
Database :
Academic Search Index
Journal :
Acta Dermato-Venereologica
Publication Type :
Academic Journal
Accession number :
126118726
Full Text :
https://doi.org/10.2340/00015555-2762