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Long-term effects of exercise at different intensity levels on depression: A randomized controlled trial.
- Source :
-
Preventive Medicine . Dec2017, Vol. 105, p37-46. 10p. - Publication Year :
- 2017
-
Abstract
- Previous research has shown positive effects of exercise on depression but studies have mainly focused on the short-term effects; few have examined the long-term effect, especially with regard to differences in intensity. The aim of this study was to examine the long-term effects of prescribed exercise on depression, performed at three intensity levels. People aged 18-67years with mild to moderate depression (Patient Health Questionnaire-9 score of ≥10) participated in a single-blind, parallel randomized control trial lasting 12weeks (Sweden 2011-2013). Four arms were included: Treatment as usual (TAU, n=310), light (n=106), moderate (n=105) and vigorous exercise (n=99). Severity of depression was measured at baseline, post-treatment and 12-month follow-up using the Montgomery-Åsberg Depression Rating Scale (MADRS). Coefficients (β) and odds ratios were estimated using linear mixed models with time×group interactions. The results showed that at the 12month follow-up the light exercise group had significantly lower depression severity scores than the TAU (-1.9, 95% CI: -3.7, -0.04) and the moderate exercise group (-2.94 95% CI: -5.2, -0.7). The vigorous exercise group had significantly lower scores than the moderate exercise group only (-2.7, 95% CI: -4.9, -0.4). In conclusion, compared to usual care for depression, only light exercise resulted in significantly lower depression severity at 12-month follow-up. Both light and vigorous exercise was more effective than moderate exercise.<bold>Trial Registration: </bold>The study was registered with the German Clinical Trial Register (DRKS study ID: DRKS00008745). [ABSTRACT FROM AUTHOR]
- Subjects :
- *PREVENTION of mental depression
*EXERCISE physiology
*RANDOMIZED controlled trials
*ODDS ratio
*DEPRESSED persons
*HEALTH
*COMPARATIVE studies
*MENTAL depression
*EXERCISE therapy
*HEALTH status indicators
*LONGITUDINAL method
*PSYCHOLOGICAL tests
*QUALITY of life
*QUESTIONNAIRES
*BLIND experiment
*SEVERITY of illness index
Subjects
Details
- Language :
- English
- ISSN :
- 00917435
- Volume :
- 105
- Database :
- Academic Search Index
- Journal :
- Preventive Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 125782733
- Full Text :
- https://doi.org/10.1016/j.ypmed.2017.08.008