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Efficient Synthesis of Highly Functionalized Spirocarbocyclic Oxindoles through Hauser Annulation.

Authors :
Lokesh, Kanduru
Kesavan, Venkitasamy
Source :
European Journal of Organic Chemistry. 10/10/2017, Vol. 2017 Issue 37, p5689-5695. 7p.
Publication Year :
2017

Abstract

The synthesis of highly functionalized spirocarbocyclic oxindoles was accomplished for the first time, using a Hauser annulation strategy. A reaction between methylene-indolinones and arylsulfonylphthalides catalyzed by cesium carbonate gave access to a new class of biologically important spiro[indoline-3,2'-naphthalene] derivatives in very good yields. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1434193X
Volume :
2017
Issue :
37
Database :
Academic Search Index
Journal :
European Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
125665005
Full Text :
https://doi.org/10.1002/ejoc.201701023