Synthesis of spiroindenyl-2-oxindoles by montmorillonite K-10-catalyzed tandem Friedel-Crafts alkenylation/hydroarylation of propargylic alcohols with sterically hindered and electron-rich arenes.

Authors :: Roh, Hwa Jung
Seo, Da Young
Ryu, Ji Yeon
Lee, Junseong
Kim, Jae Nyoung
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Oct2017, Vol. 58 Issue 43, p4094-4098. 5p.
Publication Year :: 2017
Abstract: Various spiroindenyl-2-oxindoles have been synthesized in a one-pot reaction from isatin-derived propargylic alcohols with sterically hindered and electron-rich arenes such as 2-phenylindole and 1,3,5-trimethoxybenzene. The reaction involved montmorillonite K-10-catalyzed tandem Friedel-Crafts alkenylation and a following hydroarylation of an allene intermediate. [ABSTRACT FROM AUTHOR]

Subjects :: *AROMATIC compound synthesis
*OXINDOLES
*MONTMORILLONITE
*FRIEDEL-Crafts reaction
*ALKENYLATION
*STERIC factor (Chemistry)

Language :: English
ISSN :: 00404039
Volume :: 58
Issue :: 43
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 125415840
Full Text :: https://doi.org/10.1016/j.tetlet.2017.09.035

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