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Facile Synthesis of Spirooxindole-Cyclohexenes via Phosphine-Catalyzed [4 + 2] Annulation of α-Substituted Allenoates.
- Source :
-
Chinese Journal of Chemistry . Sep2017, Vol. 35 Issue 9, p1469-1473. 5p. - Publication Year :
- 2017
-
Abstract
- A phosphine-catalyzed [4 + 2] annulation of α-substituted allenoate with exocyclic alkene moiety of oxindoles or indan-1,3-diones has been developed. Thus, under the catalysis of PPh3 (20 mol%), a series of spirooxindole- or spiroindan-1,3-dione-cyclohexenes have been obtained in moderate to excellent yields and regioselectivity from the annulations of α-methyl allenoates with 3-methyleneoxindoles or 2-methyleneindan-1,3-diones. This method offers an easy access to structurally novel spirocyclohexenes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CYCLOHEXENE
*CHEMICAL synthesis
*ANNULATION
*PHOSPHINE
*CATALYSIS
Subjects
Details
- Language :
- English
- ISSN :
- 1001604X
- Volume :
- 35
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Chinese Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 125349861
- Full Text :
- https://doi.org/10.1002/cjoc.201700112