Lipoprotein (a) - es wird Zeit, das Dornröschen wach zu küssen.

High Lp(a) concentrations are associated with cardiovascular disease (CVD) and aortic stenosis. This relationship is highly likely to be causal, as impressively demonstrated by epidemiologic and genetic studies, and is supported by firs t interventional data. Currently, the therapeutic options to lower Lp(a) are limited (with exceptions), but there is reasonable hope for the upcomingyears.The awareness is not yet well developed th at high Lp(a) concentrations can be the cause for CVD independently of other risk factors. Therefore, the «sleeping beauty» Lp(a) needs to be kissed awake and be integrated into clinical d iagnostics. In case of high Lp(a) concentrations a s tric t management of risk factors and surveillance of the patient is highly recommended. This also includes the consultation and surveillance of family members. Often the nagging question about the reason for CVD might be answered and it might be possible to avoid unnecessary suffering. [ABSTRACT FROM AUTHOR]