Synthesis of 2,3-Disubstituted 5-Iodo-1 H-Pyrrolo[2,3- b]pyridines via Fischer Cyclization.

A simple and convenient procedure for the preparation of some unknown 2,3-disubstituted 5-iodo-1 H-pyrrolo[2,3- b]pyridines from readily available starting materials by Fischer indole cyclization in polyphosphoric acid is described. The present methodology provides an alternative synthetic approach to the synthesis of 5-iodo-7-azaindole scaffold. All synthesized compounds were characterized by IR, MS, 1H and 13C NMR, and elemental analysis. [ABSTRACT FROM AUTHOR]