Core Outcome Sets (COS) for clinical trials in health- and nursing science: the case of Incontinence-Associated Dermatitis (IAD).

The article discusses the importance of clinical trials contributing to evidence-based knowledge, practice and informed clinical decision making. It is noted that the Grading of Recommendations Assessment, Development and Evaluation (GRADE) cannot be applied for the same health condition. It is noted that a crucial aspect of the design of a clinical trial is the choice of the outcome measure to be studied.