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Moyamoya Disease in Children: Results From the International Pediatric Stroke Study.
- Source :
-
Journal of Child Neurology . Oct2017, Vol. 32, p924-929. 6p. - Publication Year :
- 2017
-
Abstract
- This study aimed to describe children with moyamoya disease from an international multicenter stroke database, and explore risk factors for stroke recurrence. We reviewed data of children >28-days old with moyamoya disease enrolled in the International Pediatric Stroke Study from January 2003 to March 2013. A total of 174 children from 32 sites and 14 countries had moyamoya disease; median age 7.4 years, 49% male. Of these, 90% presented with ischemic stroke, 7.5% with transient ischemic attack, and 2.5% with hemorrhagic stroke. One-third of patients had moyamoya syndrome. Stroke recurrence was 20% over median follow-up of 13 months; 9% had multiple recurrences. Children treated with surgical revascularization were less likely to have stroke recurrence (P = .046). Moyamoya disease accounted for 8% of arterial strokes in this international pediatric stroke registry. One-third of pediatric patients with moyamoya disease have an underlying syndromic condition. Surgical revascularization is effective at reducing the incidence of stroke recurrence. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 08830738
- Volume :
- 32
- Database :
- Academic Search Index
- Journal :
- Journal of Child Neurology
- Publication Type :
- Academic Journal
- Accession number :
- 125102808
- Full Text :
- https://doi.org/10.1177/0883073817718730